Ellence

Generic Name: epirubicin (Intravenous route)

ep-i-ROO-bi-sin hye-droe-KLOR-ide

Intravenous route(Solution)

Severe local tissue necrosis will occur if there is extravasation during administration; do not administer by the IM or subQ route. Myocardial toxicity manifested in its most severe form by potentially fatal congestive heart failure (CHF) may occur either during therapy or months to years after termination of therapy. The risk of developing CHF increases rapidly with increasing total cumulative doses of epirubicin in excess of 900 mg/m(2); this cumulative dose should only be exceeded with extreme caution. Secondary acute myelogenous leukemia has been reported in patients treated with anthracyclines. Reduce dosage in patients with impaired hepatic function. Severe myelosuppression may occur with therapy .

Commonly used brand name(s)

In the U.S.

• Ellence

In Canada

• Pharmorubicin Pfs

Available Dosage Forms:

• Powder for Solution


• Solution

Therapeutic Class: Antineoplastic Agent

Chemical Class: Epirubicin

Uses For Ellence

Epirubicin injection is used together with other cancer medicines to treat cancers of the breast, lungs, lymph system, stomach, and ovaries.

Epirubicin belongs to the group of medicines called antineoplastics. It interferes with the growth of cancer cells, which are eventually destroyed. Since the growth of normal body cells may also be affected, other unwanted effects will also occur. Some of these may be serious and must be reported to your doctor. Other effects, like hair loss, may not be serious but may cause concern. Some effects may not occur until months or years after the medicine is used.

This medicine is to be administered only by or under the immediate supervision of your doctor.

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not included in the product labeling, epirubicin is used in certain patients with the following medical condition:

• Cancer of the esophagus.


• Cancer of the muscles, connective tissues (tendons), vessels that carry blood or lymph, joints, and fat.

Before Using Ellence

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of epirubicin injection in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of epirubicin injection in the elderly. However, elderly patients are more likely to have unwanted side effects, which may require caution in patients receiving epirubicin injection.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	D	Studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy in a life threatening situation or a serious disease, may outweigh the potential risk.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

• Rotavirus Vaccine, Live

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Adenovirus Vaccine Type 4, Live


• Adenovirus Vaccine Type 7, Live


• Bacillus of Calmette and Guerin Vaccine, Live


• Influenza Virus Vaccine, Live


• Measles Virus Vaccine, Live


• Mumps Virus Vaccine, Live


• Rotavirus Vaccine, Live


• Rubella Virus Vaccine, Live


• Smallpox Vaccine


• Trastuzumab


• Typhoid Vaccine


• Varicella Virus Vaccine


• Yellow Fever Vaccine

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Cimetidine


• Paclitaxel

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Congestive heart failure or


• Gout, or history of or


• Heart disease—Use with caution. May make these conditions worse.

• Heart attack, recent or


• Heart disease, severe or


• Heart rhythm problems (e.g., arrhythmia), severe or


• Liver disease, severe—Should not be used in patients with these conditions.

• Infection—May decrease your body's ability to fight an infection.

• Kidney disease or


• Liver disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.

Proper Use of epirubicin

This section provides information on the proper use of a number of products that contain epirubicin. It may not be specific to Ellence. Please read with care.

Medicines used to treat cancer are very strong and can have many unwanted effects. Before receiving this medicine, you and your doctor should talk about the benefits this medicine will do as well as the risks of using it.

A doctor or other trained health professional will give you this medicine in a hospital or cancer treatment center. This medicine is given through a needle placed in one of your veins.

This medicine must be given slowly, so the IV tube must remain in place for at least 15 to 20 minutes. It is usually given every 3 to 4 weeks.

Epirubicin is sometimes given together with other medicines. If you are receiving a combination of medicines, it is important that you receive each one at the proper time. If you are taking some of these medicines by the mouth, ask your doctor to help you plan a way to take them at the right times.

You may also receive other medicines to help prevent allergic reactions and nausea or vomiting from epirubicin.

While you are using this medicine, your doctor may want you to drink extra fluids so that you will pass more urine. This will help prevent kidney problems and keep your kidneys working well.

Precautions While Using Ellence

It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly. Blood tests may be needed to check for unwanted effects.

Your doctor may monitor your heart before you start receiving epirubicin and while you are getting treatments with this medicine. Call your doctor right away if you have any chest pain, increased coughing, trouble with breathing, a sudden difficulty with breathing at night, rapid weight gain, or abnormal swelling in your ankles or legs. These could be symptoms of serious heart problems.

This medicine should not be used within 24 weeks of stopping trastuzumab (Herceptin) unless your doctor has determined that it is the best treatment. .

This medicine can rarely cause leukemia (cancer of the blood). Talk with your doctor if you have concerns about this.

This medicine can cause birth defects if it is used by the mother while she is pregnant or by the father when his sexual partner becomes pregnant. Use an effective form of birth control to keep from getting pregnant. If a pregnancy occurs while you are using this medicine, tell your doctor right away.

While you are being treated with epirubicin, and after you stop treatment with it, do not have any immunizations (vaccinations) without your doctor's approval. Epirubicin may lower your body's resistance, and there is a chance you might get the infection the immunization is meant to prevent. In addition, you should not be around other persons living in your household who receive live virus vaccines because there is a chance they could pass the virus on to you. Some examples of live vaccines include measles, mumps, influenza (nasal flu vaccine), poliovirus (oral form), rotavirus, and rubella. Do not get close to them, and do not stay in the same room with them for very long. If you have questions about this, talk to your doctor.

Epirubicin can temporarily lower the number of white blood cells in your blood, increasing the chance of getting an infection. It can also lower the number of platelets, which are necessary for proper blood clotting. If this occurs, there are certain precautions you can take, especially when your blood count is low, to reduce the risk of infection or bleeding:

• If you can, avoid people with infections. Check with your doctor immediately if you think you are getting an infection or if you get a fever or chills, cough or hoarseness, lower back or side pain, or painful or difficult urination.


• Check with your doctor immediately if you notice any unusual bleeding or bruising; black, tarry stools; blood in the urine or stools; or pinpoint red spots on your skin.


• Be careful when using a regular toothbrush, dental floss, or toothpick. Your medical doctor, dentist, or nurse may recommend other ways to clean your teeth and gums. Check with your medical doctor before having any dental work done.


• Do not touch your eyes or the inside of your nose unless you have just washed your hands and have not touched anything else in the meantime.


• Be careful not to cut yourself when you are using sharp objects such as a safety razor or fingernail or toenail cutters.


• Avoid contact sports or other situations where bruising or injury could occur.

If epirubicin accidentally leaks out of the vein into which it is injected, it may damage some tissues and may cause scarring. Tell the doctor right away if you notice redness, pain, or swelling at the injection site.

This medicine may cause a serious type of reaction called tumor lysis syndrome. Your doctor may give you a medicine to help prevent this. Call your doctor right away if you have a decrease or change in urine amount; joint pain, stiffness, or swelling; lower back, side, or stomach pain; a rapid weight gain; swelling of the feet or lower legs; or unusual tiredness or weakness.

This medicine may turn your urine red for 1 or 2 days after your treatment. This is normal and is nothing to worry about. You may want to protect your clothing from being stained.

This medicine often causes a temporary and total loss of hair. After treatment with epirubicin has ended, normal hair growth should return.

Cancer medicines can cause nausea and vomiting, in most people, sometimes even after receiving medicines to prevent it. Ask your doctor or nurse about other ways to control these unwanted effects if you still have nausea or vomiting after receiving the medicine.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Ellence Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

• Black, tarry stools


• bleeding, redness, or ulcers in the mouth or throat


• chest pain


• cough or hoarseness


• fever or chills


• lower back or side pain


• pain or burning in the mouth or throat


• painful or difficult urination


• shortness of breath


• sore throat


• sores, ulcers, or white spots in the mouth or on the lips


• swollen glands


• unusual bleeding or bruising


• unusual tiredness or weakness

Less common

• Blood in the urine or stools


• pinpoint red spots on the skin


• red streaks along the injected vein

Rare

• Darkening or redness of the skin at place of irradiation


• difficulty with breathing


• fast or irregular heartbeat


• joint pain


• pain, redness, or warmth at the injection site


• skin rash or itching


• swelling of the abdomen or stomach, lower legs, and feet


• swelling or tenderness of the lymph nodes, abdomen, side or lower back


• wheezing

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

• Abdominal or stomach swelling or tenderness


• high fever


• stomach pain


• swelling of the lining of the mouth, nose, or throat


• vomiting

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Absent, missed, or irregular menstrual periods


• burning, dry, or itching eyes


• diarrhea


• discharge or excessive tearing


• feeling of warmth


• hair loss or thinning of the hair


• nausea


• redness of the face, neck, arms, and occasionally, upper chest


• redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid


• stopping of menstrual bleeding


• sudden sweating


• unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness

Less common

• Changes in the skin


• loss of appetite


• weight loss

Rare

• Darkening of the soles, palms, or nails

After you stop using this medicine, it may still produce some side effects that need attention. During this period of time, check with your doctor immediately if you notice the following side effects:

• Fast or irregular heartbeat


• shortness of breath


• swelling of the abdomen or stomach, feet, and lower legs

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Ellence side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More Ellence resources

• Ellence Side Effects (in more detail)
• Ellence Use in Pregnancy & Breastfeeding
• Ellence Drug Interactions
• Ellence Support Group
• 0 Reviews for Ellence - Add your own review/rating

• Ellence Prescribing Information (FDA)


• Ellence Consumer Overview


• Ellence Monograph (AHFS DI)


• Ellence MedFacts Consumer Leaflet (Wolters Kluwer)


• Epirubicin Prescribing Information (FDA)

Compare Ellence with other medications

• Breast Cancer, Adjuvant

Elite OB 400

Generic Name: prenatal multivitamins (PRE nay tal VYE ta mins)

Brand Names: Advance Care Plus, Bright Beginnings, Cavan Folate, Cavan One, Cavan-Heme OB, Cenogen Ultra, CitraNatal Rx, Co Natal FA, Complete Natal DHA, Complete-RF, CompleteNate, Concept OB, Docosavit, Dualvit OB, Duet, Edge OB, Elite OB 400, Femecal OB, Folbecal, Folcaps Care One, Folivan-OB, Foltabs, Gesticare, Icar Prenatal, Icare Prenatal Rx, Inatal Advance, Infanate DHA, Kolnatal DHA, Lactocal-F, Marnatal-F, Maternity, Maxinate, Mission Prenatal, Multi-Nate 30, Multinatal Plus, Nata 29 Prenatal, Natachew, Natafort, Natelle, Neevo, Nestabs, Nexa Select with DHA, Novanatal, NovaStart, O-Cal Prenatal, OB Complete, OB Natal One, Ob-20, Obtrex DHA, OptiNate, Paire OB Plus DHA, PNV Select, PNV-Total, PR Natal 400, Pre-H-Cal, Precare, PreferaOB, Premesis Rx, PrenaCare, PrenaFirst, PrenaPlus, Prenatabs OBN, Prenatabs Rx, Prenatal 1 Plus 1, Prenatal Elite, Prenatal Multivitamins, Prenatal Plus, Prenatal S, Prenatal-U, Prenate Advanced Formula, Prenate DHA, Prenate Elite, Prenavite FC, PreNexa, PreQue 10, Previte Rx, PrimaCare, Pruet DHA, RE OB Plus DHA, Renate, RightStep, Rovin-NV, Se-Care, Se-Natal One, Se-Plete DHA, Se-Tan DHA, Select-OB, Seton ET, Strongstart, Stuart Prenatal with Beta Carotene, Tandem OB, Taron-BC, Tri Rx, TriAdvance, TriCare, Trimesis Rx, Trinate, Triveen-PRx RNF, UltimateCare Advance, Ultra-Natal, Vemavite PRX 2, VeNatal FA, Verotin-BY, Verotin-GR, Vinacal OR, Vinatal Forte, Vinate Advanced (New Formula), Vinate AZ, Vinate Care, Vinate Good Start, Vinate II (New Formula), Vinate III, Vinate One, Vitafol-OB, VitaNatal OB plus DHA, Vitaphil, Vitaphil Aide, Vitaphil Plus DHA, Vitaspire, Viva DHA, Vol-Nate, Vol-Plus, Vol-Tab Rx, Vynatal F.A., Zatean-CH, Zatean-PN

What are Elite OB 400 (prenatal multivitamins)?

There are many brands and forms of prenatal vitamin available and not all brands are listed on this leaflet.

Prenatal vitamins are a combination of many different vitamins that are normally found in foods and other natural sources.

Prenatal vitamins are used to provide the additional vitamins needed during pregnancy. Minerals may also be contained in prenatal multivitamins.

Prenatal vitamins may also be used for purposes not listed in this medication guide.

What is the most important information I should know about prenatal vitamins?

There are many brands and forms of prenatal vitamin available and not all brands are listed on this leaflet.

Never take more than the recommended dose of a multivitamin. Avoid taking any other multivitamin product within 2 hours before or after you take your prenatal vitamins. Taking similar vitamin products together at the same time can result in a vitamin overdose or serious side effects.

Many multivitamin products also contain minerals such as calcium, iron, magnesium, potassium, and zinc. Minerals (especially taken in large doses) can cause side effects such as tooth staining, increased urination, stomach bleeding, uneven heart rate, confusion, and muscle weakness or limp feeling. Read the label of any multivitamin product you take to make sure you are aware of what it contains.

Seek emergency medical attention if you think you have used too much of this medicine. An overdose of vitamins A, D, E, or K can cause serious or life-threatening side effects and can also harm your unborn baby. Certain minerals contained in a prenatal multivitamin may also cause serious overdose symptoms or harm to the baby if you take too much.

Overdose symptoms may include stomach pain, vomiting, diarrhea, constipation, loss of appetite, hair loss, peeling skin, tingly feeling in or around your mouth, changes in menstrual periods, weight loss, severe headache, muscle or joint pain, severe back pain, blood in your urine, pale skin, and easy bruising or bleeding.

Do not take this medication with milk, other dairy products, calcium supplements, or antacids that contain calcium. Calcium may make it harder for your body to absorb certain ingredients of the multivitamin.

What should I discuss with my healthcare provider before taking prenatal vitamins?

Many vitamins can cause serious or life-threatening side effects if taken in large doses. Do not take more of this medication than directed on the label or prescribed by your doctor.

Before taking prenatal vitamins, tell your doctor about all of your medical conditions.

You may need to continue taking prenatal vitamins if you breast-feed your baby. Ask your doctor about taking this medication while breast-feeding.

How should I take prenatal vitamins?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Never take more than the recommended dose of prenatal vitamins.

Many multivitamin products also contain minerals such as calcium, iron, magnesium, potassium, and zinc. Minerals (especially taken in large doses) can cause side effects such as tooth staining, increased urination, stomach bleeding, uneven heart rate, confusion, and muscle weakness or limp feeling. Read the label of any multivitamin product you take to make sure you are aware of what it contains.

Take your prenatal vitamin with a full glass of water.

Swallow the regular tablet or capsule whole. Do not break, chew, crush, or open it.

The chewable tablet must be chewed or allowed to dissolve in your mouth before swallowing. You may also allow the chewable tablet to dissolve in drinking water, fruit juice, or infant formula (but not milk or other dairy products). Drink this mixture right away.

Use prenatal vitamins regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.

Store at room temperature away from moisture and heat. Keep prenatal vitamins in their original container. Storing vitamins in a glass container can ruin the medication.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine. An overdose of vitamins A, D, E, or K can cause serious or life-threatening side effects and can also harm your unborn baby. Certain minerals contained in a prenatal multivitamin may also cause serious overdose symptoms or harm to the baby if you take too much.

Overdose symptoms may include stomach pain, vomiting, diarrhea, constipation, loss of appetite, hair loss, peeling skin, tingly feeling in or around your mouth, changes in menstrual periods, weight loss, severe headache, muscle or joint pain, severe back pain, blood in your urine, pale skin, and easy bruising or bleeding.

What should I avoid while taking prenatal vitamins?

Avoid taking any other multivitamin product within 2 hours before or after you take your prenatal vitamins. Taking similar vitamin products together at the same time can result in a vitamin overdose or serious side effects.

Avoid the regular use of salt substitutes in your diet if your multivitamin contains potassium. If you are on a low-salt diet, ask your doctor before taking a vitamin or mineral supplement.

Do not take this medication with milk, other dairy products, calcium supplements, or antacids that contain calcium. Calcium may make it harder for your body to absorb certain ingredients of the prenatal vitamin.

Prenatal vitamins side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

When taken as directed, prenatal vitamins are not expected to cause serious side effects. Less serious side effects may include:

• 
  

  upset stomach;

  
  


• 
  

  headache; or

  
  


• 
  

  unusual or unpleasant taste in your mouth.

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect prenatal vitamins?

Vitamin and mineral supplements can interact with certain medications, or affect how medications work in your body. Before taking a prenatal vitamin, tell your doctor if you also use:

• 
  

  diuretics (water pills);

  
  


• 
  

  heart or blood pressure medications;

  
  


• 
  

  tretinoin (Vesanoid);

  
  


• 
  

  isotretinoin (Accutane, Amnesteen, Clavaris, Sotret);

  
  


• 
  

  trimethoprim and sulfamethoxazole (Cotrim, Bactrim, Gantanol, Gantrisin, Septra, TMP/SMX); or

  
  


• 
  

  an NSAID (non-steroidal anti-inflammatory drug) such as ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn, Naprelan, Treximet), celecoxib (Celebrex), diclofenac (Cataflam, Voltaren), indomethacin (Indocin), meloxicam (Mobic), and others.

  
  

This list is not complete and other drugs may interact with prenatal vitamins. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More Elite OB 400 resources

• Elite OB 400 Use in Pregnancy & Breastfeeding
• Elite OB 400 Drug Interactions
• 0 Reviews for Elite OB 400 - Add your own review/rating

• Cal-Nate MedFacts Consumer Leaflet (Wolters Kluwer)


• CareNatal DHA MedFacts Consumer Leaflet (Wolters Kluwer)


• CitraNatal 90 DHA MedFacts Consumer Leaflet (Wolters Kluwer)


• CitraNatal Assure Prescribing Information (FDA)


• CitraNatal Harmony Prescribing Information (FDA)


• Concept DHA Prescribing Information (FDA)


• Docosavit Prescribing Information (FDA)


• Duet DHA with Ferrazone MedFacts Consumer Leaflet (Wolters Kluwer)


• Folbecal MedFacts Consumer Leaflet (Wolters Kluwer)


• Folcal DHA Prescribing Information (FDA)


• Folcaps Care One Prescribing Information (FDA)


• Gesticare DHA Prescribing Information (FDA)


• Gesticare DHA MedFacts Consumer Leaflet (Wolters Kluwer)


• Inatal Advance Prescribing Information (FDA)


• Inatal Ultra Prescribing Information (FDA)


• Multi-Nate DHA Prescribing Information (FDA)


• Multi-Nate DHA Extra Prescribing Information (FDA)


• MultiNatal Plus MedFacts Consumer Leaflet (Wolters Kluwer)


• Natelle One Prescribing Information (FDA)


• Neevo Caplets MedFacts Consumer Leaflet (Wolters Kluwer)


• Neevo DHA MedFacts Consumer Leaflet (Wolters Kluwer)


• OB Complete 400 MedFacts Consumer Leaflet (Wolters Kluwer)


• Paire OB Plus DHA Prescribing Information (FDA)


• PreNexa MedFacts Consumer Leaflet (Wolters Kluwer)


• PreNexa Prescribing Information (FDA)


• PreferaOB Prescribing Information (FDA)


• Prenatal Plus Prescribing Information (FDA)


• Prenatal Plus Iron Prescribing Information (FDA)


• Prenate Elite Prescribing Information (FDA)


• Prenate Elite MedFacts Consumer Leaflet (Wolters Kluwer)


• Prenate Elite tablets


• Prenate Essential Prescribing Information (FDA)


• PrimaCare Advantage MedFacts Consumer Leaflet (Wolters Kluwer)


• PrimaCare ONE capsules


• PrimaCare One MedFacts Consumer Leaflet (Wolters Kluwer)


• Renate DHA Prescribing Information (FDA)


• Se-Natal 19 Chewable Tablets MedFacts Consumer Leaflet (Wolters Kluwer)


• Se-Natal 19 Prescribing Information (FDA)


• Tandem DHA Prescribing Information (FDA)


• Tandem OB Prescribing Information (FDA)


• TriAdvance Prescribing Information (FDA)


• Triveen-One MedFacts Consumer Leaflet (Wolters Kluwer)


• Triveen-PRx RNF Prescribing Information (FDA)


• UltimateCare ONE NF Prescribing Information (FDA)


• Ultra NatalCare MedFacts Consumer Leaflet (Wolters Kluwer)


• Vinate AZ Prescribing Information (FDA)


• Vitafol-One MedFacts Consumer Leaflet (Wolters Kluwer)


• Zatean-CH Prescribing Information (FDA)

Compare Elite OB 400 with other medications

• Vitamin/Mineral Supplementation during Pregnancy/Lactation

Where can I get more information?

• Your pharmacist can provide more information about prenatal vitamins.

Serevent Diskus inhalation

Generic Name: salmeterol (inhalation) (sal MEE ter all)

Brand Names: Serevent Diskus

What is Serevent Diskus (salmeterol (inhalation))?

Salmeterol is a bronchodilator. It works by relaxing muscles in the airways to improve breathing.

Salmeterol inhalation is used to prevent asthma attacks. It will not treat an asthma attack that has already begun. Salmeterol inhalation is also used to treat chronic obstructive pulmonary disease (COPD) including emphysema and chronic bronchitis.

Salmeterol inhalation may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Serevent Diskus (salmeterol (inhalation))?

Do not use salmeterol inhalation to treat an asthma attack that has already begun. Salmeterol may increase the risk of asthma-related death. Use only the prescribed dose of this medication, and do not use it for longer than your doctor recommends. Follow all patient instructions for safe use. Talk with your doctor about your individual risks and benefits of using salmeterol inhalation.

Asthma is often treated with a combination of different drugs. If you use salmeterol inhalation to treat asthma, you must use it together with another asthma control medication. Use all of your medications as directed by your doctor. Talk with your doctor if your medications do not seem to work as well in treating or preventing attacks. Do not change your doses or medication schedule without advice from your doctor.

Do not use a second form of salmeterol (such as Advair) or use a similar inhaled bronchodilator such as formoterol or arformoterol (Foradil, Perforomist, Symbicort, or Brovana) unless your doctor has told you to.

Seek medical attention if you think any of your asthma medications are not working as well as usual. An increased need for medication could be an early sign of a serious asthma attack. If you use a peak flow meter at home, call your doctor if your numbers are lower than normal.

What should I discuss with my healthcare provider before using Serevent Diskus (salmeterol (inhalation))?

You should not use this medication if you are allergic to salmeterol. If you have asthma, salmeterol inhalation should not be your only asthma medication. You must use it together with at least one other asthma control medication.

If you have any of these other conditions, you may need a dose adjustment or special tests:

• 
  

  a food or drug allergy;

  
  


• 
  

  heart disease or high blood pressure;

  
  


• 
  

  epilepsy or other seizure disorder;

  
  


• 
  

  diabetes;

  
  


• 
  

  a thyroid disorder; or

  
  


• liver disease.

FDA pregnancy category C. It is not known whether salmeterol inhalation will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether salmeterol inhalation passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not give this medication to a child younger than 4 years old.

How should I use Serevent Diskus (salmeterol (inhalation))?

Salmeterol may increase the risk of asthma-related death. Use only the prescribed dose of this medication, and do not use it for longer than your doctor recommends. Follow all patient instructions for safe use. Tell your doctor if your symptoms do not improve after 1 week of treatment. Do not use salmeterol inhalation to treat an asthma attack that has already begun. It will not work fast enough. Use only a fast-acting inhalation medication.

Asthma is often treated with a combination of different drugs. If you use salmeterol inhalation to treat asthma, you must use it together with another asthma control medication. Use all of your medications as directed by your doctor. Talk with your doctor if your medications do not seem to work as well in treating or preventing attacks. Do not change your doses or medication schedule without advice from your doctor.

If you are using salmeterol inhalation to prevent exercise-induced asthma, use the medicine 30 minutes before exercising, or as directed by your doctor. Allow at least 12 hours to pass before you use the medicine again.

Serevent Diskus is a powder form of salmeterol inhalation that comes with a special inhaler device preloaded with blister packs containing measured doses of the medicine. The device opens and loads a blister each time you use the inhaler. This device is not to be used with a spacer.

Use salmeterol inhalation regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.

Do not stop using salmeterol inhalation without first talking to your doctor. Your asthma symptoms may get worse after you stop using the medication. If you also use a steroid medication, do not stop using the steroid suddenly or you may have unpleasant withdrawal symptoms. Talk with your doctor about taking less and less of the steroid before stopping completely. Seek medical attention if you think any of your asthma medications are not working as well as usual. An increased need for medication could be an early sign of a serious asthma attack. If you use a peak flow meter at home, call your doctor if your numbers are lower than normal. Store at room temperature away from moisture, heat, and sunlight.

Do not try to clean or take apart the Diskus device. Throw it away 6 weeks after you have taken it out of the foil pouch, or if the dose indicator shows a zero, whichever comes first. Each Diskus device contains 60 doses.

What happens if I miss a dose?

Use the medication as soon as you remember, then wait 12 hours before using the medication again. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include muscle cramps, dry mouth, sleep problems (insomnia), tremors, chest pain, fast or irregular heartbeats, feeling light-headed, fainting, or seizure (convulsions).

What should I avoid while using Serevent Diskus (salmeterol (inhalation))?

Do not use a second form of salmeterol (such as Advair) or use a similar inhaled bronchodilator such as formoterol or arformoterol (Foradil, Perforomist, Symbicort, or Brovana) unless your doctor has told you to.

Do not exhale or blow into the Diskus device. Do not take the device apart or allow it to get wet.

Serevent Diskus (salmeterol (inhalation)) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:

• 
  

  chest pain, fast or pounding heartbeats, tremors, shaking, or restless feeling;

  
  


• 
  

  skin rash, bruising, severe tingling, numbness, pain, muscle weakness;

  
  


• 
  

  wheezing, choking, or other breathing problems after using this medication; or

  
  


• 
  

  worsening asthma symptoms.

  
  

Less serious side effects may include:

• 
  

  headache, dizziness, lightheadedness, or insomnia;

  
  


• 
  

  sweating;

  
  


• 
  

  nausea, vomiting, or diarrhea; or

  
  


• 
  

  dry mouth or throat irritation.

  
  

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Serevent Diskus (salmeterol (inhalation))?

Before using salmeterol inhalation, tell your doctor if you are using any of the following drugs:

• 
  

  a diuretic (water pill);

  
  


• 
  

  an antibiotic such as clarithromycin (Biaxin) or telithromycin (Ketek);

  
  


• 
  

  an antibiotic such as clarithromycin (Biaxin) or telithromycin (Ketek);

  
  


• 
  

  a beta-blocker such as atenolol (Tenormin, Tenoretic), carvedilol (Coreg), labetalol (Normodyne, Trandate), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), sotalol (Betapace), and others;

  
  


• 
  

  an antidepressant such as amitriptyline (Elavil), nefazodone, nortriptyline (Pamelor), desipramine (Norpramin), or imipramine (Tofranil);

  
  


• 
  

  HIV or AIDS medication such as atazanavir (Reyataz), indinavir (Crixivan), ritonavir (Norvir, Kaletra), nelfinavir (Viracept), or saquinavir (Invirase);

  
  


• 
  

  an MAO inhibitor such as isocarboxazid (Marplan), tranylcypromine (Parnate), phenelzine (Nardil), or selegiline (Eldepryl, Emsam);

  
  


• 
  

  caffeine, a diet medicine, or a decongestant; or

  
  


• 
  

  aminophylline (Truphylline), theophylline (Elixophyllin, Theo-24, Uniphyl), and others.

  
  

This list is not complete and other drugs may interact with salmeterol inhalation. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More Serevent Diskus resources

• Serevent Diskus Side Effects (in more detail)
• Serevent Diskus Use in Pregnancy & Breastfeeding
• Serevent Diskus Drug Interactions
• Serevent Diskus Support Group
• 0 Reviews for Serevent Diskus - Add your own review/rating

Compare Serevent Diskus with other medications

• Asthma, Maintenance
• Bronchospasm Prophylaxis
• COPD, Maintenance

Where can I get more information?

• Your pharmacist can provide more information about salmeterol inhalation.

See also: Serevent Diskus side effects (in more detail)

pilocarpine

pye-loe-KAR-peen

Commonly used brand name(s)

In the U.S.

• Salagen

Available Dosage Forms:

• Tablet

Therapeutic Class: Dental Agent

Pharmacologic Class: Cholinergic

Uses For pilocarpine

Pilocarpine tablets are used to treat dryness of the mouth and throat caused by a decrease in the amount of saliva that may occur after radiation treatment for cancer of the head and neck or in patients with Sjogren's syndrome. pilocarpine may help you speak without having to sip liquids. It may also help with chewing, tasting, and swallowing. pilocarpine may reduce your need for other oral comfort agents, such as hard candy, sugarless gum, or artificial saliva agents.

Pilocarpine may also be used to treat dryness of the eyes caused by Sjogren's syndrome

pilocarpine is available only with your doctor's prescription.

Before Using pilocarpine

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For pilocarpine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to pilocarpine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Studies on pilocarpine have been done only in adult patients and there is no specific information comparing use of pilocarpine in children with use in other age groups.

Geriatric

pilocarpine has been tested and has not been shown to cause different side effects or problems in older people than it does in younger adults.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of pilocarpine. Make sure you tell your doctor if you have any other medical problems, especially:

• Asthma, bronchitis, or other breathing problems, or


• Gallbladder problems or


• Glaucoma, angle closure, or


• Heart or blood vessel disease or


• Iritis (inflammation of the iris [colored part] of the eye) or


• Kidney problems or


• Mental problems or


• Peptic ulcer disease, acute—Pilocarpine may make the condition worse

• Retinal detachment, tendency for, or


• Retinal disease—Pilocarpine may increase the risk of a detached retina

Proper Use of pilocarpine

Take pilocarpine only as directed. Do not take it more often and do not take a larger dose than directed. To do so may increase the chance of side effects.

It is important that you visit your dentist regularly even though pilocarpine may make your dry mouth feel better. Having a dry mouth condition makes you more likely to have dental and other mouth problems.

Dosing

The dose of pilocarpine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of pilocarpine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For oral dosage form (tablets):
  
  • For dryness of eyes:
    
    • Adults—5 milligrams (mg) three or four times a day.
    
    
  
  
  • For dryness of mouth and throat:
    
    • Adults—5milligrams (mg) three or four times a day.
    
    
    • Children—Use and dose must be determined by your doctor.
    
    
  
  

Missed Dose

If you miss a dose of pilocarpine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using pilocarpine

pilocarpine may cause difficulty in reading or other vision problems, especially at night. It may also cause some people to become dizzy or lightheaded. Make sure you know how you react to pilocarpine before you drive, use machines, or do anything else that could be dangerous if you are not alert or able to see well. If these reactions are especially bothersome, check with your doctor.

pilocarpine may cause you to sweat more than is usual. If you do, it is important that you drink extra liquids to offset this sweating so you do not lose too much fluid and become dehydrated. Check with your doctor if you are not sure how much extra liquid to drink or if you cannot drink as much liquid as you should.

pilocarpine Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

Symptoms of overdose

• Chest pain


• confusion


• diarrhea (continuing or severe)


• fainting


• fast, slow, or irregular heartbeat (continuing or severe)


• headache (continuing or severe)


• nausea or vomiting (continuing or severe)


• shortness of breath or troubled breathing


• stomach cramps or pain


• tiredness or weakness (continuing or severe)


• trembling or shaking (continuing or severe)


• trouble seeing (continuing or severe)

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Chills


• cough


• diarrhea


• feeling of warmth or heat


• fever


• flushing or redness of skin especially on face and neck


• increased need to urinate


• indigestion


• joint pain


• muscle aches and pains


• nausea


• passing urine more often


• runny nose


• unusual tiredness or weakness


• Sweating

Less common or rare

• fast heartbeat


• headache


• holding more body water


• swelling of face, fingers, ankles, or feet


• trembling or shaking


• trouble swallowing


• trouble seeing


• unusual weak feeling


• voice change


• vomiting

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More pilocarpine resources

• Pilocarpine Dosage
• Pilocarpine Use in Pregnancy & Breastfeeding
• Drug Images
• Pilocarpine Drug Interactions
• Pilocarpine Support Group
• 0 Reviews for Pilocarpine - Add your own review/rating

• pilocarpine Concise Consumer Information (Cerner Multum)


• Pilocarpine Prescribing Information (FDA)


• Pilocarpine Monograph (AHFS DI)


• Pilocarpine Professional Patient Advice (Wolters Kluwer)


• Pilocarpine MedFacts Consumer Leaflet (Wolters Kluwer)


• Salagen Prescribing Information (FDA)

Compare pilocarpine with other medications

• Xerostomia

Fluzone 2011-2012 injection

Generic Name: influenza virus vaccine (injection) (in floo ENZ a VYE rus VAK seen)

Brand Names: Afluria 2011-2012, Afluria Preservative-Free 2011-2012, Fluarix 2010-2011, Fluarix 2011-2012, FluLaval 2011-2012, Fluvirin 2011-2012, Fluvirin Preservative-Free 2011-2012, Fluzone 2011-2012, Fluzone High-Dose 2011-2012, Fluzone Intradermal 2011-2012, Fluzone Preservative-Free 2011-2012, Fluzone Preservative-Free Pediatric 2011-2012

What is influenza virus vaccine?

Influenza virus (commonly known as "the flu") is a serious disease caused by a virus. Influenza virus can spread from one person to another through small droplets of saliva that are expelled into the air when an infected person coughs or sneezes. The virus can also be passed through contact with objects the infected person has touched, such as a door handle or other surfaces.

Influenza virus vaccine is used to prevent infection caused by influenza virus. The vaccine is redeveloped each year to contain specific strains of inactivated (killed) flu virus that are recommended by public health officials for that year.

The injectable influenza virus vaccine (flu shot) is a "killed virus" vaccine. Influenza virus vaccine is also available in a nasal spray form, which is a "live virus" vaccine.

Influenza virus vaccine works by exposing you to a small dose of the virus, which helps your body to develop immunity to the disease. Influenza virus vaccine will not treat an active infection that has already developed in the body.

Influenza virus vaccine is for use in adults and children who are at least 6 months old.

Becoming infected with influenza is much more dangerous to your health than receiving this vaccine. Influenza causes thousands of deaths each year, and hundreds of thousands of hospitalizations. However, like any medicine, this vaccine can cause side effects but the risk of serious side effects is extremely low.

Like any vaccine, influenza virus vaccine may not provide protection from disease in every person. This vaccine will not prevent illness caused by avian flu ("bird flu").

What is the most important information I should know about this vaccine?

The injectable influenza virus vaccine (flu shot) is a "killed virus" vaccine. Influenza virus vaccine is also available in a nasal spray form, which is a "live virus" vaccine. This medication guide addresses only the injectable form of this vaccine.

You can still receive a vaccine if you have a minor cold. In the case of a more severe illness with a fever or any type of infection, wait until you get better before receiving this vaccine.

Keep track of any and all side effects you have after receiving this vaccine. If you ever need to receive influenza virus vaccine in the future, you will need to tell your doctor if the previous shot caused any side effects.

Like any vaccine, influenza virus vaccine may not provide protection from disease in every person. This vaccine will not prevent illness caused by avian flu ("bird flu").

Influenza virus injectable (killed virus) vaccine will not cause you to become ill with the flu virus that it contains. However, you may have flu-like symptoms at any time during flu season that may be caused by other strains of influenza virus.

Becoming infected with influenza is much more dangerous to your health than receiving this vaccine. However, like any medicine, this vaccine can cause side effects but the risk of serious side effects is extremely low.

What should I discuss with my healthcare provider before receiving this vaccine?

You should not receive this vaccine if you have ever had an allergic reaction to a flu vaccine, or if you have:

• 
  

  an active or uncontrolled neurologic disorder (such as Parkinson's disease, Alzheimer's disease, or epilepsy);

  
  


• 
  

  a history of seizures;

  
  


• 
  

  a history of Guillian-Barre syndrome (within 6 weeks after receiving a vaccine);

  
  


• 
  

  if you are allergic to eggs.

  
  

To make sure you can safely receive this vaccine, tell your doctor if you have any of these other conditions:

• 
  

  a bleeding or blood clotting disorder such as hemophilia or easy bruising;

  
  


• 
  

  a neurologic disorder or disease affecting the brain (or if this was a reaction to a previous vaccine);

  
  


• 
  

  a weak immune system caused by disease, bone marrow transplant, or by using certain medicines or receiving cancer treatments; or

  
  


• 
  

  if you are allergic to latex rubber.

  
  

You can still receive a vaccine if you have a minor cold. In the case of a more severe illness with a fever or any type of infection, wait until you get better before receiving this vaccine.

Vaccines may be harmful to an unborn baby and generally should not be given to a pregnant woman. However, not vaccinating the mother could be more harmful to the baby if the mother becomes infected with a disease that this vaccine could prevent. Your doctor will decide whether you should receive this vaccine, especially if you have a high risk of infection with influenza. It is not known whether influenza virus vaccine passes into breast milk or if it could harm a nursing baby. Do not receive this vaccine without telling your doctor if you are breast-feeding a baby. This vaccine should not be given to a child younger than 6 months old.

How is this vaccine given?

Some brands of this vaccine are made for use in adults and not in children. Your child's doctor can recommend the best influenza virus vaccine for your child.

This vaccine is given as an injection (shot) into a muscle. You will receive this injection in a doctor's office or other clinic setting.

You should receive a flu vaccine every year. Your immunity will gradually decrease over the 12 months after you receive the influenza virus vaccine. Children receiving this vaccine may need a booster shot one month after receiving the first vaccine.

The influenza virus vaccine is usually given in October or November. Some people may need to have their vaccines earlier or later. Follow your doctor's instructions.

Your doctor may recommend treating fever and pain with an aspirin-free pain reliever such as acetaminophen (Tylenol) or ibuprofen (Motrin, Advil, and others) when the shot is given and for the next 24 hours. Follow the label directions or your doctor's instructions about how much of this medicine to give your child.

It is especially important to prevent fever from occurring in a child who has a seizure disorder such as epilepsy.

What happens if I miss a dose?

Since flu shots are usually given only one time per year, you will most likely not be on a dosing schedule. Call your doctor if you forget to receive your yearly flu shot in October or November.

If your child misses a booster dose of this vaccine, call your doctor for instructions.

What happens if I overdose?

An overdose of this vaccine is unlikely to occur.

What should I avoid before or after receiving this vaccine?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Influenza virus injectable vaccine side effects

Influenza virus injectable (killed virus) vaccine will not cause you to become ill with the flu virus that it contains. However, you may have flu-like symptoms at any time during flu season that may be caused by other strains of influenza virus.

You should not receive a booster vaccine if you had a life-threatening allergic reaction after the first shot. Keep track of any and all side effects you have after receiving this vaccine. If you ever need to receive influenza virus vaccine in the future, you will need to tell your doctor if the previous shot caused any side effects. Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as:

• 
  

  severe weakness or unusual feeling in your arms and legs (may occur 2 to 4 weeks after you receive the vaccine);

  
  


• 
  

  high fever;

  
  


• 
  

  seizure (convulsions); or

  
  


• 
  

  unusual bleeding.

  
  

Less serious side effects may include:

• 
  

  low fever, chills;

  
  


• 
  

  mild fussiness or crying;

  
  


• 
  

  redness, bruising, pain, swelling, or a lump where the vaccine was injected;

  
  


• 
  

  headache, tired feeling; or

  
  


• 
  

  joint or muscle pain.

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report vaccine side effects to the US Department of Health and Human Services at 1-800-822-7967.

What other drugs will affect influenza virus injectable vaccine?

Before receiving this vaccine, tell your doctor if you are using phenytoin (Dilantin), theophylline (Respbid, Slo-Bid, Theodur, Uniphyl), or a blood thinner (warfarin, Coumadin, Jantoven).

Also tell the doctor if you have recently received drugs or treatments that can weaken the immune system, including:

• 
  

  an oral, nasal, inhaled, or injectable steroid medicine;

  
  


• 
  

  medications to treat psoriasis, rheumatoid arthritis, or other autoimmune disorders, such as azathioprine (Imuran), etanercept (Enbrel), leflunomide (Arava), and others; or

  
  


• 
  

  medicines to treat or prevent organ transplant rejection, such as basiliximab (Simulect), cyclosporine (Sandimmune, Neoral, Gengraf), muromonab-CD3 (Orthoclone), mycophenolate mofetil (CellCept), sirolimus (Rapamune), or tacrolimus (Prograf).

  
  

If you are using any of these medications, you may not be able to receive the vaccine, or may need to wait until the other treatments are finished.

This list is not complete and other drugs may interact with influenza virus vaccine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More Fluzone 2011-2012 resources

• Fluzone 2011-2012 Use in Pregnancy & Breastfeeding
• Fluzone 2011-2012 Drug Interactions
• Fluzone 2011-2012 Support Group
• 1 Review for Fluzone 2011-2012 - Add your own review/rating

Compare Fluzone 2011-2012 with other medications

• Influenza Prophylaxis

Where can I get more information?

• Your doctor or pharmacist can provide more information about this vaccine. Additional information is available from your local health department or the Centers for Disease Control and Prevention.

eptifibatide

Generic Name: eptifibatide (ep ti FYE ba tide)

Brand Names: Integrilin

What is eptifibatide?

Eptifibatide keeps the platelets in your blood from coagulating (clotting) to prevent unwanted blood clots that can occur with certain heart or blood vessel conditions.

Eptifibatide is used to prevent blood clots or heart attack in people with severe chest pain or other conditions, and in those who are undergoing a procedure called angioplasty (to open blocked arteries).

Eptifibatide may also be used for purposes not listed in this medication guide.

What is the most important information I should know about eptifibatide?

You should not receive this medication if you are allergic to eptifibatide, if you have or will soon receive treatment with similar medications such as abciximab (ReoPro) or tirofiban (Aggrastat).

You should not receive this medication if you have severe or uncontrolled high blood pressure, if you are on dialysis due to kidney failure, history of a bleeding or blood clotting disorder, if you had a stroke or any type of bleeding within the past 30 days, or if you had any type of surgery, injury, or medical emergency within the past 6 weeks.

Eptifibatide is not expected to be harmful to an unborn baby. However, aspirin is sometimes given with eptifibatide, and aspirin can cause bleeding when it is taken during the last 3 months of pregnancy. Aspirin can also cause side effects in a newborn baby.

Tell your doctor if you are pregnant or plan to become pregnant during treatment with eptifibatide and aspirin.

Because eptifibatide keeps your blood from coagulating (clotting) to prevent unwanted blood clots, it can also make it easier for you to bleed, even from a minor injury. Contact your doctor or seek emergency medical attention if you have bleeding that will not stop.

What should I discuss with my health care provider before receiving eptifibatide?

You should not receive this medication if you are allergic to eptifibatide, if you have or will soon receive treatment with similar medications such as abciximab (ReoPro) or tirofiban (Aggrastat), or if you have:

• 
  

  kidney failure and you are on dialysis;

  
  


• 
  

  severe or uncontrolled high blood pressure;

  
  


• 
  

  history of a bleeding or blood clotting disorder, such as hemophilia or thrombocytopenia;

  
  


• 
  

  if you have had a stroke or any type of bleeding within the past 30 days; or

  
  


• 
  

  if you have had any type of surgery, injury, or medical emergency within the past 6 weeks.

  
  

To make sure you can safely receive eptifibatide, tell your doctor if you have kidney disease.

FDA Pregnancy Category B. Eptifibatide is not expected to be harmful to an unborn baby. However, aspirin is sometimes given with eptifibatide, and aspirin can cause bleeding when it is taken during the last 3 months of pregnancy. Aspirin can also cause side effects in a newborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether eptifibatide passes into breast milk or if it could harm a nursing baby. Do not receive this medication without telling your doctor if you are breast-feeding a baby.

How is eptifibatide given?

Eptifibatide is injected into a vein through an IV. You will receive this injection in a clinic or hospital setting. Eptifibatide is sometimes given around the clock for up to 4 days in a row.

If you are receiving this injection during an angioplasty procedure, the medicine will be given throughout the entire procedure and for up to 24 hours after the procedure.

Eptifibatide is sometimes given together with aspirin. Follow your doctor's instructions about how much aspirin to take and for how long.

To be sure this medicine is helping your condition and is not causing harmful effects, your blood will need to be tested often. Visit your doctor regularly.

Because eptifibatide keeps your blood from coagulating (clotting) to prevent unwanted blood clots, it can also make it easier for you to bleed, even from a minor injury. Contact your doctor or seek emergency medical attention if you have bleeding that will not stop.

What happens if I miss a dose?

Since eptifibatide is given by a healthcare professional, you are not likely to miss a dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include severe forms of some of the side effects listed in this medication guide.

What should I avoid while receiving eptifibatide?

Avoid activities that may increase your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth.

Avoid drinking alcohol. It may increase your risk of bleeding in your stomach or intestines.

Eptifibatide side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as:

• 
  

  easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;

  
  


• 
  

  blood in your urine;

  
  


• 
  

  black, bloody, or tarry stools;

  
  


• 
  

  coughing up blood or vomit that looks like coffee grounds;

  
  


• 
  

  any bleeding that will not stop;

  
  


• 
  

  sudden numbness or weakness, especially on one side of the body;

  
  


• 
  

  sudden severe headache, confusion, problems with vision, speech, or balance;

  
  


• 
  

  fever, chills, body aches, flu symptoms; or

  
  


• 
  

  feeling like you might pass out.

  
  

Less serious side effects may also occur, such as:

• 
  

  nausea;

  
  


• 
  

  upset stomach; or

  
  


• 
  

  bleeding around the IV needle.

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Eptifibatide Dosing Information

Usual Adult Dose for Myocardial Infarction:

Initial: 180 mcg/kg intravenous bolus administered as soon as possible following diagnosis
Maintenance: 2 mcg/kg/min continuous infusion (following the initial bolus) until hospital discharge or initiation of CABG surgery, up to 72 hours. If a patient is to undergo a percutaneous coronary intervention (PCI) while receiving eptifibatide, the infusion should be continued up to hospital discharge, or for up to 18 to 24 hours after the procedure, whichever comes first, allowing for up to 96 hours of therapy.

In patients who undergo coronary artery bypass graft surgery, eptifibatide infusion should be discontinued prior to surgery.

Usual Adult Dose for Angina Pectoris:

Initial: 180 mcg/kg intravenous bolus administered as soon as possible following diagnosis
Maintenance: 2 mcg/kg/min continuous infusion (following the initial bolus) until hospital discharge or initiation of CABG surgery, up to 72 hours. If a patient is to undergo a percutaneous coronary intervention (PCI) while receiving eptifibatide, the infusion should be continued up to hospital discharge, or for up to 18 to 24 hours after the procedure, whichever comes first, allowing for up to 96 hours of therapy.

In patients who undergo coronary artery bypass graft surgery, eptifibatide infusion should be discontinued prior to surgery.

Usual Adult Dose for Acute Coronary Syndrome:

Initial: 180 mcg/kg intravenous bolus administered as soon as possible following diagnosis
Maintenance: 2 mcg/kg/min continuous infusion (following the initial bolus) until hospital discharge or initiation of CABG surgery, up to 72 hours. If a patient is to undergo a percutaneous coronary intervention (PCI) while receiving eptifibatide, the infusion should be continued up to hospital discharge, or for up to 18 to 24 hours after the procedure, whichever comes first, allowing for up to 96 hours of therapy.

In patients who undergo coronary artery bypass graft surgery, eptifibatide infusion should be discontinued prior to surgery.

Usual Adult Dose for Percutaneous Coronary Intervention:

Initial: 180 mcg/kg intravenous bolus administered immediately before the initiation of PCI followed by a continuous infusion of 2 mcg/kg/min and a second 180 mcg/kg bolus 10 minutes after the first bolus. Infusion should be continued until hospital discharge, or for up to 18 to 24 hours, whichever comes first. A minimum of 12 hours of infusion is recommended by the manufacturer. Alternatively, an infusion duration of 16 hours may be appropriate as noted in the ESPRIT substudy.

In patients who undergo coronary artery bypass graft surgery, eptifibatide infusion should be discontinued prior to surgery.

What other drugs will affect eptifibatide?

Tell your doctor about all other medicines you use, especially:

• 
  

  a blood thinner such as warfarin (Coumadin, Jantoven), heparin, ardeparin (Normiflo), dalteparin (Fragmin), danaparoid (Orgaran), enoxaparin (Lovenox), fondaparinux (Arixtra), or tinzaparin (Innohep);

  
  


• 
  

  drugs that dissolve blood clots, such as alteplase (Activase), tenecteplase (TNKase), urokinase (Abbokinase);

  
  


• 
  

  medicines that keep blood platelets from clumping together, such as anagrelide (Agrylin), cilostazol (Pletal), clopidogrel (Plavix), dipyridamole (Persantine, Aggrenox), prasugrel (Effient), ticlopidine (Ticlid); or

  
  


• 
  

  medicines that block the action of a blood-clotting enzyme, such as argatroban (Acova), dabigatran (Pradaxa), bivalirudin (Angiomax), lepirudin (Refludan).

  
  

This list is not complete and other drugs may interact with eptifibatide. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More eptifibatide resources

• Eptifibatide Side Effects (in more detail)
• Eptifibatide Dosage
• Eptifibatide Use in Pregnancy & Breastfeeding
• Eptifibatide Drug Interactions
• Eptifibatide Support Group
• 1 Review for Eptifibatide - Add your own review/rating

• eptifibatide Intravenous Advanced Consumer (Micromedex) - Includes Dosage Information


• Eptifibatide Professional Patient Advice (Wolters Kluwer)


• Eptifibatide MedFacts Consumer Leaflet (Wolters Kluwer)


• Eptifibatide Monograph (AHFS DI)


• Integrilin Prescribing Information (FDA)


• Integrilin Consumer Overview

Compare eptifibatide with other medications

• Acute Coronary Syndrome
• Angina
• Heart Attack
• Percutaneous Coronary Intervention

Where can I get more information?

• Your doctor or pharmacist can provide more information about eptifibatide.

See also: eptifibatide side effects (in more detail)

Scalacort DK topical

Generic Name: hydrocortisone, salicylic acid, and sulfur (topical) (HYE droe KOR ti sone, SAL i SIL ik AS id, and SUL fur (TOP i kal))

Brand Names: Coraz, Scalacort DK

What is hydrocortisone, salicylic acid, and sulfur?

Hydrocortisone is in a class of drugs called steroids. Hydrocortisone prevents the release of substances in the body that cause inflammation.

Salicylic acid and sulfur topical (for the skin) work together to soften scales and psoriasis plaques and cause shedding of the outer layer of skin.

The combination of hydrocortisone, salicylic acid, and sulfur is used to treat inflammation, itching, flaking, scaling, and other symptoms of scalp psoriasis or seborrheic dermatitis.

This medication is supplied as a kit containing hydrocortisone lotion, salicylic acid and sulfur shampoo, and a cleansing shampoo.

Hydrocortisone, salicylic acid, and sulfur may also be used for purposes not listed in this medication guide.

What is the most important information I should know about hydrocortisone, salicylic acid, and sulfur?

This combination product comes as a kit that includes hydrocortisone lotion, a medicated shampoo containing both salicylic acid and sulfur, and a gentle cleansing shampoo. Carefully follow the directions for use of the three products.

You should not use this medication if you are allergic to hydrocortisone, salicylic acid, or sulfur.

To make sure you can safely use this medication, tell your doctor about all of your medical conditions.

Do not use hydrocortisone, salicylic acid, and sulfur to treat any skin condition that has not been checked by your doctor. This medication will not treat a bacterial, fungal, or viral skin infection. Do not use this medication on a child without a doctor's advice. Children are more sensitive to the effects of hydrocortisone topical.

Although the risk of serious side effects is low when hydrocortisone is applied to the skin, side effects can occur if the medication is absorbed into your bloodstream.

What should I discuss with my health care provider before using hydrocortisone, salicylic acid, and sulfur?

You should not use this medication if you are allergic to hydrocortisone, salicylic acid, or sulfur.

To make sure you can safely use this medication, tell your doctor about all of your medical conditions.

Also tell your doctor if you have diabetes. Topical steroid medicines absorbed through the skin may increase the glucose (sugar) levels in your blood or urine.

Hydrocortisone topical will not treat a bacterial, fungal, or viral skin infection.

FDA pregnancy category C. It is not known whether hydrocortisone, salicylic acid, and sulfur will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether hydrocortisone, salicylic acid, and sulfur passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not use this medication on a child without a doctor's advice. Children are more sensitive to the effects of hydrocortisone topical. Hydrocortisone can affect growth in children. Talk with your doctor if you think your child is not growing at a normal rate while using this medication.

How should I use hydrocortisone, salicylic acid, and sulfur?

Use exactly as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Topical steroid medicine can be absorbed through the skin, which may cause steroid side effects throughout the body.

This combination product comes as a kit that includes hydrocortisone lotion, a medicated shampoo containing both salicylic acid and sulfur, and a gentle cleansing shampoo. Carefully follow the directions for use of the three products.

You may wash your hair daily with the gentle cleansing shampoo. The medicated shampoo may be used on the scalp, chest, back, or other affected areas. Follow your doctor's instructions about how often to use the medicated shampoo.

Wash your hands before and after applying the hydrocortisone lotion.

Apply the lotion in a thin film and rub in gently. It should dry quickly.

Do not cover treated skin areas with a bandage or other covering unless your doctor has told you to. Covering skin that is treated with hydrocortisone topical can increase the amount of the drug your skin absorbs, which may lead to unwanted side effects. Follow your doctor's instructions.

Call your doctor if your symptoms do not improve, or if they get worse while using this medication.

Do not use hydrocortisone, salicylic acid, and sulfur to treat any skin condition that has not been checked by your doctor. Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Since this medication is used as needed, you may not be on a dosing schedule. If you are using the medication regularly, use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Long-term use of high steroid doses can lead to symptoms such as thinning skin, easy bruising, changes in the shape or location of body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.

What should I avoid while using hydrocortisone, salicylic acid, and sulfur?

Avoid getting this medication in your eyes. If this does happen, rinse with water.

Avoid using other medications on the areas you treat with hydrocortisone, salicylic acid, and sulfur unless you doctor tells you to.

Hydrocortisone, salicylic acid, and sulfur side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have severe skin irritation after applying this medication.

Although the risk of serious side effects is low when hydrocortisone is applied to the skin, you should be aware of side effects that can occur if the medication is absorbed into your bloodstream.

• 
  

  headaches, back aches, weakness, confusion;

  
  


• 
  

  weight gain, roundness in your face;

  
  


• 
  

  increased acne or facial hair, itching or irritation around your mouth;

  
  


• 
  

  swelling, warmth, redness, oozing, or other signs of infection;

  
  


• 
  

  changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist);

  
  


• 
  

  menstrual problems (in women), impotence or loss of interest in sex (in men); or

  
  


• 
  

  high blood sugar (increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, weight loss).

  
  

Less serious side effects may include:

• 
  

  mild burning, itching, or irritation;

  
  


• 
  

  dryness or peeling of treated skin;

  
  


• 
  

  redness or crusting around hair follicles;

  
  


• 
  

  color changes in treated skin;

  
  


• 
  

  thinning of your skin; or

  
  


• 
  

  stretch marks.

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect hydrocortisone, salicylic acid, and sulfur?

It is not likely that other drugs you take orally or inject will have an effect on topically applied hydrocortisone, salicylic acid, and sulfur. But many drugs can interact with each other. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More Scalacort DK resources

• Scalacort DK Side Effects (in more detail)
• Scalacort DK Use in Pregnancy & Breastfeeding
• Scalacort DK Drug Interactions
• 0 Reviews for Scalacort DK - Add your own review/rating

Compare Scalacort DK with other medications

• Seborrheic Dermatitis

Where can I get more information?

• Your pharmacist can provide more information about hydrocortisone, salicylic acid, and sulfur.

See also: Scalacort DK side effects (in more detail)